Patient Videos

Clinical Trials in Melanoma

Doug's story: Why did you decide to take part in a clinical trial for your melanoma?
Doug shares his personal story of why he decided to participate in a clinical trial for his melanoma. After speaking with his care team about his melanoma treatment options, he was matched to a clinical trial that best fit the phase of melanoma he was experiencing. He also describes some of the successes he had in the trial.
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Kristina's story: Why did you decide to take part in a clinical trial for your melanoma?
Kristina discusses why she decided to participate in a clinical trial when her melanoma recurred and after having a discussion with her doctor. Being part of research that advances melanoma treatment was very appealing to her. She also describes how she found the clinical trial that she joined as well as the informed consent process.
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Doug's story: What was the clinical trial enrollment process like for you?
Doug describes the process of how he enrolled in a melanoma clinical trial. The process was very thorough and involved baseline testing so that his progress could be measured during the trial. He also explains the informed consent process that provided detailed information about the clinical trial.
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Kristina's story: What was the clinical trial enrollment process like for you?
Kristina shares what the melanoma clinical trial enrollment process was like for her. She received a lot of attention and support from her medical team, had baseline testing, and signed the consent form to participate in the trial. During the informed consent process, she was well-informed about the risks and benefits of participating in the trial.
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Doug's story: What was your overall experience during and after the melanoma clinical trial?
Doug describes his experience during and after participating in the melanoma clinical trial. He shares that there were challenges, but his outcome was ultimately successful. Doug says he would participate in a trial again knowing that he would be well cared for.
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Kristina's story: What was your overall experience during and after the melanoma clinical trial?
Kristina shares her overall experience in the melanoma clinical trial. While she did experience some side effects, she received a lot of care, management, and monitoring from her medical team. She has no regrets and would be glad to participate in a clinical trial again.
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Doug's story: What advice do you have for others about taking part in melanoma clinical trials?
Doug shares advice and practical tips for others who may want to take part in a melanoma clinical trial. He talks about the importance of educating yourself, asking questions, and getting as much clarity as possible about the treatments that are available. He also recommends having a caregiver with you during the enrollment process to help with understanding the information provided.
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Kristina's story: What advice do you have for others about taking part in melanoma clinical trials?
Kristina shares her advice for others with melanoma who are thinking about taking part in a clinical trial. She believes clinical trials are a great way to seek treatment beyond the current standard of care and encourages others to seriously think about clinical trial participation. If you're thinking about a clinical trial, Kristina recommends seeking information from organizations like the Melanoma Research Foundation.
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Metastatic Uveal Melanoma

Ashley's story: How did you find out you had metastatic uveal melanoma?
Ashley explains that after years of routine monitoring following her original uveal melanoma diagnosis, routine scans in 2020 revealed metastatic disease in her liver. She describes quickly starting specialized care, including liver-directed therapies, clinical trials, and ongoing systemic treatment, which together helped control the cancer and significantly reduce her tumors.
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Ashley's story: What advice do you have for others on their journey with metastatic uveal melanoma?
Ashley encourages people newly diagnosed with metastatic uveal melanoma to seek care at a Center of Excellence with specialists experienced in this rare disease. She stresses the importance of expert guidance, second opinions, and access to clinical trials, as well as finding reliable information to avoid feeling isolated and to make confident treatment decisions. Ashley also shares that she runs the Eye on Grace Foundation that funds treatment-related travel for those diagnosed with uveal melanoma.
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Jon's story: How did you find out you had metastatic uveal melanoma?
Jon shares that after years of regular scans following his original uveal melanoma diagnosis, a routine MRI found a small tumor in his liver, showing the cancer had spread. Because his metastatic uveal melanoma was caught early, he was able to receive targeted liver treatments, join a clinical trial, and later use additional therapies to manage tumors in other parts of his body.
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Jon's story: What advice do you have for others on their journey with metastatic uveal melanoma?
Jon encourages people with metastatic uveal melanoma to plan ahead and build a strong care team they trust. He emphasizes working with experienced doctors who understand the disease, staying informed about treatment options, and keeping up with regular scans. Having a clear plan, he says, helps patients feel prepared and ready to move quickly when treatment decisions are needed.
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This educational activity has been developed by the Melanoma Research Foundation (MRF) and Mechanisms in Medicine Inc.

This activity is supported by independent educational grants from Bristol-Myers Squibb, Foundation Medicine, Genentech, Immunocore, Iovance Biotherapeutics, Merck, Natera, Novartis, and Replimune.

This website is part of the Animated Patient® series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.